#29: Jane Leeves as Daphne Moon Crane, Frasier
Daphne Moon wasn’t technically a mom when she arrived on Frasier, but by the time the show wrapped, she’d become one — and in her own quirky, lovable way. The psychic housekeeper from Manchester brought warmth and chaos into Frasier’s world, balancing Niles’s neurotic energy with heart and humor.

Jane Leeves made Daphne feel like the sitcom’s emotional anchor. Amidst the witty wordplay and highbrow banter, she brought real humanity. Her chemistry with David Hyde Pierce was lightning in a bottle — awkward, tender, and timeless. When Daphne finally got her happy ending, fans everywhere cheered.
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